數百年來,橄欖一直是健康飲食的一部分。人們認為吃橄欖和橄欖油是生活在地中海地區的人享受長壽健康生活的關鍵原因。

Olivol®是一種富含抗氧化多酚(一種植物中的有機化學物質)的提取物,完全來自橄欖果。

在橄欖(Olea europaea L.)中發現的多酚抗氧化劑不存在於其他常見的膳食來源中。它們在結構上不同於水果和蔬菜中的維生素,類胡蘿蔔素,生物類黃酮,原花色素和其他抗氧化劑。這些抗氧化劑可能是地中海飲食中與健康和長壽相關的成分之一。

羥基酪醇是橄欖果中的主要抗氧化劑,據信它在橄欖油的許多健康益處中起著重要作用*:

  • 研究已將該化合物與心血管益處聯繫起來,通常支持健康的膽固醇水平(已經在正常範圍內)和健康的血液循環。*
  • 有限的數據表明該化合物可能有助於眼睛健康。*
  • 許多研究表明,由於其能夠中和高反應性自由基,它可以幫助支持DNA,線粒體(您的細胞能量植物)和其他細胞結構免受氧化應激。*
  • 關於膳食營養素影響細胞信號傳導能力的新興研究發現,橄欖果實化合物可以刺激選擇的分子途徑。這包括與天然強效抗氧化劑如穀胱甘肽的生產相關的那些。用羥基酪醇靶向細胞信號通路已顯示出保護大腦,心血管,皮膚健康等方面的前景。*

資料來源:

Vázquez-Velasco M, et al. 2011. Effects of hydroxytyrosol-enriched sunflower oil consumption on CVD risk factors. Br J Nutr. 105(10):1448-52.

Deiana M, et al. 1999. Inhibition of peroxynitrite dependent DNA base modification and tyrosine nitration by the extra virgin olive oil-derived antioxidant hydroxytyrosol. Free Radic Biol Med 26(5-6): 762-9.

Fabiani R, et al. 2008. Oxidative DNA damage is prevented by extracts of olive oil, hydroxytyrosol, and other olive phenolic compounds in human blood mononuclear cells and HL60 cells. J Nutr 138(8): 1411-6.

Manna C, et al. 1999. Olive oil hydroxytyrosol protects human erythrocytes against oxidative damages. J Nutr Biochem 10(3):159-65.

St-Laurent-Thibault C, Arseneault M, Longpre F, Ramassamy C. 2011. Tyrosol and hydroxytyrosol, two main components of olive oil, protect N2a cells against amyloid-β-induced toxicity. Involvement of the NF-κB signaling. Curr Alz Res 8(5): 543-551(9).

Omar SH, Scott CJ, Hamlin AS, Obied HK. 2018. Biophenols: Enzymes (β-secretase, Cholinesterases, histone deacetylase and tyrosinase) inhibitors from olive (Olea europaea L.). Fitoterapia 128: 118-129.

Hao J, et al. 2010. Hydroxytyrosol promotes mitochondrial biogenesis and mitochondrial function in 3T3-L1 adipocytes. J Nutr Biochem 21(7): 634-44.

Peyrol J, Riva C, Amiot MJ. 2017. Hydroxytyrosol in the Prevention of the Metabolic Syndrome and Related Disorders. Nutrients. 9(3): 306.

de Las Hazas MCL, Rubio L, Macia A, Motilva MJ. 2018. Hydroxytyrosol: Emerging trends in potential therapeutic applications. Curr Pharm Des [Internet] [accessed 10 July 2018] Available at https://www.ncbi.nlm.nih.gov/pubmed/29788874

Calabriso N, et al. 2018. Hydroxytyrosol Ameliorates Endothelial Function under Inflammatory Conditions by Preventing Mitochondrial Dysfunction. Oxid Med Cell Longev [Internet] [accessed 10 July 2018] Available at https://www.ncbi.nlm.nih.gov/pubmed/29849923

Ghanbari R, et al. 2012. Valuable Nutrients and Functional Bioactives in Different Parts of Olive (Olea europaea L.)—A Review. Int J Mol Sci 13(3): 3291-3340.

Vilaplana-Pérez C, Auñon D, Garcia-Flores LA, Gil-Izquierdo A. 2014. Hydroxytyrosol and Potential Uses in Cardiovascular Diseases, Cancer, and AIDS. Front Nutr 1:18.

Zhu L, et al. 2010. Hydroxytyrosol protects against oxidative damage by simultaneous activation of mitochondrial biogenesis and phase II detoxifying enzyme systems in retinal pigment epithelial cells. J Nutr Biochem 21(11): 1089-98.

Zou X, et al. 2012. Stimulation of GSH synthesis to prevent oxidative stress-induced apoptosis by hydroxytyrosol in human retinal pigment epithelial cells: activation of Nrf2 and JNK-p62/SQSTM1 pathways. J Nutr Biochem 23(8): 994-1006.